October 18

5 Reasons to Have Your Grandparents on Mushrooms

by Dr. Dov Pine

My grandparents use medicinal mushrooms regularly and I am convinced yours should too! Over the last two years my Sabim (grandparents) have been taking medicinal mushrooms like Reishi, Lion’s Mane, Turkey Tail and Chaga in their coffee. As a natural medicine, the health properties of medicinal mushrooms are extensive, but more importantly safe for the older generation. Here are 5 reasons you should show your family love by bringing medicinal mushrooms to your grandparent’s kitchen.

5 Reasons To Get Your Grandparents On Medicinal Mushrooms

My grandparents add up to 1/2 a tsp of our medicinal mushroom extract into their morning coffee every day.

I don’t know about your grandparents, but mine have had their share of health issues. Heart issues, atherosclerosis, pneumonia, muscle wasting, macular degeneration, pleural effusion and so on. Thank goodness they are relatively healthy and stable now. Right now, age is the main factor working against them. My grandfather is 97 and my grandmother is 90. That means big lifestyle changes, even smaller ones are troublesome to implement. Adding quality to their life has always been a priority for me. The toughest part is keeping it simple.

Every year when I visit my grandparents overseas, I bring them a bag of medicinal mushroom powder for them to use in their morning coffee. Ironically, the mushrooms sit in the kitchen counter alongside their daily prescription medications. It’s picture worthy.

For years now, they have been happy to put their grandson’s brown mushroom powder in their brew while they read the daily news.  Here are 5 reasons why I make sure they do.

When you can’t shift the paradigm, give it the support it needs.

Medicinal mushrooms and brain health

Brain health is priority number one. The Lion’s Mane mushroom (Hericium erinaceus) has well documented brain health promoting properties that have been researched in conditions such as mild cognitive impairment and memory loss.1,2 Traditionally used in the countries of east Asia, its neurotrophic or nerve growth inducing properties have been the subject of research in methods for naturally supporting health in patients with Alzheimer’s and Parkinson’s disease.2,3 Keeping in mind, this is not a cure or treatment.

In the case of Alzheimer’s studies, Lion’s Mane has the effect of reducing beta-amyloid plaque formation, one of the main factors involved in this unfortunate and widespread condition.2 In a Parkinson’s disease study, the Lion’s Mane mushroom has been demonstrated to reduce the degenerative effects on an area of the brain called the substantia nigra, part of the basal ganglia.3 This is the region in the brain affected by Parkinson’s disease. Much more research is necessary aside from in vitro and mice studies. The Lion’s Mane mushroom nonetheless has unique brain and nervous system health properties and oddly enough, even looks like a brainy mass.

The Turkey Tail mushroom (Trametes versicolor) has brain antioxidant properties which may also contribute to maintaining neurological health.4 Brain health is reason number one to have your grandparents taking mushrooms.

Heart and Circulatory Health

Statistically speaking, heart disease is the leading cause of death. Cardiovascular and circulatory system health decline with age, there is no way around it. The culprit is atherosclerosis. Arteries clog over the years resulting from long term inflammation and cholesterol imbalances. It is rare in this day and age to find people in their 60’s and beyond not prescribed on heart or cholesterol medications especially if you live in any Western country.

Renowned physicians like Neil Barnard MD, Michael Greger MD, and Michael Klapper MD teach that a whole foods plant based diet can reverse many of these effects. True indeed, but if it is difficult for the regular day individual to change their diet and lifestyle it can be even more of a challenge for the senior generation.

Three main factors lead to heart attacks and stroke – lipid metabolism, coagulation and platelet aggregation (metabolism of fats, increase in blood viscosity and clotting). The end result is elevated blood pressure, cholesterol levels and clotting complications. Lion’s Mane mushroom studies show heart protective qualities that reduce blood cholesterol levels, blood pressure and reduce vascular clotting.5,6,7 Nature seems to have the health needs of our older generation in mind with this mushroom.

Anti-Depression and Anti-Anxiety

An inevitable component of the aging process involves slowing down in movement, metabolic function, and vitality levels. It is a fact of life that certainly has its emotional challenges. Positive mental outlook and stress reduction have obvious implications in this department. Reishi and Lion’s Mane mushrooms can help.

Reishi mushroom (Ganoderma lucidum) has been utilized in Traditional Chinese Medicine and Asian countries for promoting health and longevity as well as treating many clinical conditions. As an adaptogen, Reishi mushrooms have anti-depressant, anti-anxiety and energy promoting effects.8-10 Lion’s Mane mushrooms also have antidepressant-like effects. A 2010 study demonstrated a reduction of depression and anxiety within 4 weeks among participants who consumed Lion’s Mane cookies versus placebo.11 I am a cookie lover- it is always joyful to eat cookies, but in this case the placebo group was not as long lasting! On to reason number four.

Anti-Cancer

Research on medicinal mushrooms has been devoted to their potential anti-cancer effects including slowing tumor growth, regulating tumor genes and stimulating the immune system to better fight cancer. Medicinal mushrooms even protect healthy cells from the toxic effects of chemotherapy drugs without inhibiting the chemotherapy and radiation effects on cancer cells.12

The anti-cancer properties found in medicinal mushrooms such as Reishi, Chaga, Turkey Tail are due to their ability to stimulate T-Helper 1 or TH1 production. This refers to an immune response in which the immune system creates more soldiers, surveillance and tactics (tumor-specific antigens, tumoricidal cytokines, Natural Killer cells, CD8+T cells and tumoricidal macrophages)12 to identify, seek out and destroy cancer cells.

More research is warranted. However, here are some of the findings reviewed for this article. Anti-cancer activity has been demonstrated in Reishi mushroom studies with breast and ovarian cancer,13, 14,15 lung cancers such as pulmonary adenocarcinoma,16 liver cancers,17,18 bladder cancer,19 leukemia, lymphoma and multiple myeloma20  and colorectal cancer.21 Fungi including Lion’s Mane, Chaga and Turkey Tail have researched effects in hepatocellular carcinoma,22 leukemia,23,24  brain cancer,25  breast cancer,26,27 colon cancer,28 melanoma,29  and lung cancer.30 In addition, these mushrooms have a protective effect against chemotherapy immunological weakness. At the very least, this offers a potential immune support to patients undergoing conventional cancer treatment with chemotherapy.12

Bone Density Support

Osteoporosis is a widespread age-related chronic disease. Combined with balance issues, one bad fall can easily break a wrist, shoulder or hip. I remember during a family dinner my Nana fell and broke her hip. I must have been 8 years old. It is a difficult recovery for most and may often lead to complications. Turkey Tail mushrooms, though commonly revered for their anti-cancer properties demonstrate effects in protecting against bone resorption (osteoclast production) and improving bone density and formation.31,32 If this property isn’t old age appropriate, I am not sure what is. Reason number five!

How My Grandparents Take Medicinal Mushrooms

It couldn’t be easier- I have them use at least half ½ a teaspoon of a blend of reishi, chaga, turkey tail and lion’s mane in their coffee every day. Simple, stress free and no added effort.

Disclaimer. The information represented in this article is meant to provide concepts from evidence based research. It is not intended to treat or diagnose any health condition. For appropriate treatment methods please contact your healthcare provider. 

1. Mori K et al. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res.2009 Mar;23(3):367-72.
2. Mori K et al. Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Biomed Res.2011 Feb;32(1):67-72.
3. Kuo et al. Hericium erinaceusmycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade J of Translational Medicine. 2016;14:(78)
4. Chen J et al. A study on the antioxidant effect of Coriolus versicolor polysaccharide in rat brain tissues. Afr J Tradit Complement Altern Med.2013 Oct 3;10(6):481-4.
5. Mori K et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.2010 Dec 1;17(14):1082
6. Hiwatashi K et al. Yamabushitake mushroom (Hericium erinaceus) improved lipid metabolism in mice fed a high-fat diet. Biosci Biotechnol Biochem.2010;74(7):1447-51.
7. Mori K et al. The Anti-Inflammatory Effects of Lion’s Mane Culinary-Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) in a Coculture System of 3T3-L1 Adipocytes and RAW264 Macrophages. Int J Med Mushrooms.2015;17(7):609-18
8. Matsuzaki H et al. Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats. BMC Complement Altern Med. 2013 Dec 26;13:370.
9. Singh R, et al. Evaluation of Antianxiety Potential of Four Ganoderma (Agaricomycetes) Species from India in MiceInt J Med Mushrooms.2016;18(11):991-998.
10. Tang W. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurastheniaJ Med Food.2005 Spring;8(1):53-8.
11. Nagano M et al. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res.2010 Aug;31(4):231-7.
12. Guggenheim AG et al.Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44.
13. Suarez-Arroyo IJ et al. Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models. PLoS One. 2013;8(2):e57431.
14. Jiang J et al.Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-kappaB signaling.Nutr Cancer.2004;49(2):209-16.
15. Hsieh TC,Wu JM.Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3. Int J Mol Med. 2011 Dec;28(6):1065-9.
16. Kashimoto N et al.Inhibitory effect of a water-soluble extract from the culture medium of Ganoderma lucidum (Rei-shi) mycelia on the development of pulmonary adenocarcinoma induced by N-nitrosobis (2-hydroxypropyl) amine in Wistar rats. Oncol Rep.2006 Dec;16(6):1181-7.
17. Weng CJ et al.Inhibitory effects of ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models. J Agric Food Chem.2009 Jun 10;57(11):5049-57.
18. Aimei Li et al.Ganoderma lucidum polysaccharide extract inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation and function by inducing microRNA-125b. J Transl Med. 2015; 13: 100.
19. Lu QY et al.Ganoderma lucidum extracts inhibit growth and induce actin polymerization in bladder cancer cells in vitro.Cancer Lett.2004 Dec 8;216(1):9-20.
20. Müller CI et al.Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells. Leuk2006 Jul;30(7):841-8.
21. Dan X et al.A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells. Front Pharmacol.2016 Jul 25;7:217.
22. Lee JS, Hong EK. Hericium erinaceus enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells.Cancer Lett. 2010 Nov 28;297(2):144-54.
23. Kim SP et al. Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells. Food Funct. 2011 Jun;2(6):348-56.
24. Hsieh TC et al. Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by the combination of Coriolus versicolor and Ganoderma lucidum.Int J Mol Med. 2013 Jul;32(1):251-7.
25. Ning X et al. Inhibitory effects of a polysaccharide extract from the Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), on the proliferation of human neurogliocytoma cells.Int J Med Mushrooms. 2014;16(1):29-36.
26. Chung MJ et al. Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells. Nutr Res Pract. 2010 Jun;4(3):177-82.
27. Standish LJ et al. Trametes versicolor mushroom immune therapy in breast cancer.J Soc Integr Oncol.2008 Summer;6(3):122-8.
28. Lee HS et al. Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells.Nutr Res Pract.2015 Apr;9(2):111-6.
29. Lee KR et al. Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-κB signaling pathway.Mol Med Rep. 2016 Nov;14(5):4429-4435.
30. Lee KR et al. Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9. Int J Oncol.2014 Dec;45(6):2533-40.
31. Chen CH et al. Polysaccharides of Trametes versicolor Improve Bone Properties in Diabetic Rats.J Agric Food Chem.2015 Oct 28;63(42):9232-8.
32. Erjavec I et al. Mushroom Extracts Decrease Bone Resorption and Improve Bone Formation. Int J Med Mushrooms. 2016;18(7):559-69.

About the author

Dr. Dov Pine

Dov is a Chiropractor and Applied Kinesiologist with a clinical focus in health restoration and individual potential through Meaning and Responsible Action. Dr. Pine lives in Newcastle, New South Wales and attends patients at Chiropractic Plus in New Lambton and Warners Bay.

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Medicinal Mushrooms – Topic

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